Most typically, I will base my comments on a very recent article in the scientific literature. I'm shooting for one of these article-based commentaries ("Journal clubs") per week. Minor entries will be interspersed as I feel inspired.
I anticipate errors and correction, and I'll post corrections prominently.
Theology, philosophy and Shakespeare will also figure semi-prominently. I don't really care about politics, so it won't often contaminate the blog unless and until a politician speaks on a topic of interest. (And, of course, they often do.) Boston Red Sox baseball will always trump politics.
So, here's Hamlet getting the first big quote (ripped unceremoniously out of context):
"...there is something in this more than natural, if philosophy could find it out."
--Hamlet, Act II, Scene II